Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope.


Journal Article

Microscopy with nonlinear phase contrast is achieved by a simple modification to a nonlinear pump-probe microscope. The technique measures cross-phase modulation by detecting a pump-induced spectral shift in the probe pulse. Images with nonlinear phase contrast are acquired both in transparent and absorptive media. In paraffin-embedded biopsy sections, cross-phase modulation complements the chemically-specific pump-probe images with structural context.

Full Text

Duke Authors

Cited Authors

  • Wilson, JW; Samineni, P; Warren, WS; Fischer, MC

Published Date

  • May 2012

Published In

Volume / Issue

  • 3 / 5

Start / End Page

  • 854 - 862

PubMed ID

  • 22567580

Pubmed Central ID

  • 22567580

Electronic International Standard Serial Number (EISSN)

  • 2156-7085

International Standard Serial Number (ISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/BOE.3.000854


  • eng