Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia.

Journal Article (Clinical Trial;Journal Article)

In a recent landmark trial of bacteremia caused by methicillin-resistant Staphylococcus aureus (MRSA) isolates, vancomycin MICs were >or=1 microg/ml for only 16% of the isolates, and accessory gene regulator (agr) function as measured by delta-hemolysin activity was absent or reduced in only 28.1% of the isolates. This clinical study did not capture a population of MRSA isolates predictive of vancomycin treatment failure.

Full Text

Duke Authors

Cited Authors

  • McCalla, C; Smyth, DS; Robinson, DA; Steenbergen, J; Luperchio, SA; Moise, PA; Fowler, VG; Sakoulas, G

Published Date

  • September 2008

Published In

Volume / Issue

  • 52 / 9

Start / End Page

  • 3441 - 3443

PubMed ID

  • 18606839

Pubmed Central ID

  • PMC2533503

Electronic International Standard Serial Number (EISSN)

  • 1098-6596

Digital Object Identifier (DOI)

  • 10.1128/AAC.00357-08


  • eng

Conference Location

  • United States