Management of methicillin-resistant Staphylococcus aureus bacteremia.

Journal Article (Journal Article;Review)

Staphylococcus aureus bacteremia and endocarditis are serious infections that demand prompt clinical attention to ensure good outcomes. Of foremost importance is identifying and managing the source of infection and any associated complications. Evaluation for the presence of cardiac involvement is essential because inadequately managed S. aureus endocarditis is life threatening. Thus, physicians must aggressively negotiate treatment paths, considering whether the S. aureus bacteremia is complicated, whether foreign sources of infection should be removed or replaced, and whether surgical intervention is necessary. Selection of an antibiotic treatment is also an essential factor for optimal management. The increasing prevalence of methicillin-resistant S. aureus (MRSA) infections has created a tremendous demand for effective and safe antimicrobial agents other than the historic anti-MRSA agent vancomycin.

Full Text

Duke Authors

Cited Authors

  • Cosgrove, SE; Fowler, VG

Published Date

  • June 1, 2008

Published In

Volume / Issue

  • 46 Suppl 5 /

Start / End Page

  • S386 - S393

PubMed ID

  • 18462094

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

Digital Object Identifier (DOI)

  • 10.1086/533595


  • eng

Conference Location

  • United States