First reported case of infective endocarditis caused by community-acquired methicillin-resistant Staphylococcus aureus not associated with healthcare contact in Brazil.

Journal Article (Journal Article)

We report here the first case of endocarditis due to CA-MRSA not associated with healthcare contact in Brazil in Brazil. A previously healthy patient presented with history of endocarditis following a traumatic wound infection. Patient had multiple positive blood cultures within 72 h of admission and met modified Duke's criterion for infective endocarditis. The isolate was typed as Staphylococcal cassette chromosome (SCC) mec type IV and was positive for presence of Panton-Valentine leukocidin (PVL). Increased incidence of CA-MRSA endocarditis is a challenge for the internist to choose the best empirical therapy. Several authors have suggested an empirical therapy with both a beta-lactam and an anti-MRSA agent for serious S. aureus infections. Our patient was treated with Vancomycin and made complete recovery in 3 months.

Full Text

Duke Authors

Cited Authors

  • Fortes, CQ; Espanha, CA; Bustorff, FP; Zappa, BC; Ferreira, ALP; Moreira, RB; Pereira, NG; Fowler, VG; Deshmukh, H

Published Date

  • December 2008

Published In

Volume / Issue

  • 12 / 6

Start / End Page

  • 541 - 543

PubMed ID

  • 19287847

Electronic International Standard Serial Number (EISSN)

  • 1678-4391

Digital Object Identifier (DOI)

  • 10.1590/s1413-86702008000600020


  • eng

Conference Location

  • Brazil