Postoperative nausea and vomiting following the use of fentanyl or remifentanil in ambulatory gynecologic laparoscopic surgery: A prospective randomized trial

Journal Article (Journal Article)

Purpose: To test the hypothesis that using remifentanil during nitrous oxide-sevoflurane anesthetic would be associated with less postoperative nausea and vomiting (PONV) compared to a similar technique with fentanyl. Scope: Sixty patients undergoing outpatient gynecologic laparoscopy were randomly assigned to remifentanil or fentanyl for intraoperative analgesia. The complete response rate (no PONV and no rescue) was 50% / 29 % in the remifentanil group and 37% / 12 % in the fentanyl group in the PACU and at 24 hours respectively (p=ns). Conclusion: The use of remifentanil was not associated with a reduction in the incidence of PONV, compared with fentanyl, in patients undergoing ambulatory gynecologic laparoscopy.

Duke Authors

Cited Authors

  • Habib, AS; Muir, HA; Schultz, JR; Olufolabi, AJ; White, WD; Gan, TJ

Published Date

  • March 1, 2007

Published In

Volume / Issue

  • 13 / 1

International Standard Serial Number (ISSN)

  • 0966-6532

Citation Source

  • Scopus