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Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme.

Publication ,  Journal Article
MacDonald, MR; Petrie, MC; Varyani, F; Ostergren, J; Michelson, EL; Young, JB; Solomon, SD; Granger, CB; Swedberg, K; Yusuf, S; Pfeffer, MA ...
Published in: Eur Heart J
June 2008

AIMS: To determine whether the risk of adverse cardiovascular (CV) outcomes associated with diabetes differs in patients with low and preserved ejection fraction (EF) heart failure (HF). METHODS AND RESULTS: We analysed outcomes in the Candesartan in Heart failure-Assessment of Reduction in Mortality and morbidity (CHARM) programme which randomized 7599 patients with symptomatic HF and a broad range of EF. The prevalence of diabetes was 28.3% in patients with preserved EF (>40%) and 28.5% in those with low EF (

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Published In

Eur Heart J

DOI

EISSN

1522-9645

Publication Date

June 2008

Volume

29

Issue

11

Start / End Page

1377 / 1385

Location

England

Related Subject Headings

  • Treatment Outcome
  • Tetrazoles
  • Stroke Volume
  • Prognosis
  • Male
  • Humans
  • Heart Failure
  • Female
  • Epidemiologic Methods
  • Diabetic Angiopathies
 

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MacDonald, M. R., Petrie, M. C., Varyani, F., Ostergren, J., Michelson, E. L., Young, J. B., … CHARM Investigators, . (2008). Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme. Eur Heart J, 29(11), 1377–1385. https://doi.org/10.1093/eurheartj/ehn153
MacDonald, Michael R., Mark C. Petrie, Fumi Varyani, Jan Ostergren, Eric L. Michelson, James B. Young, Scott D. Solomon, et al. “Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme.Eur Heart J 29, no. 11 (June 2008): 1377–85. https://doi.org/10.1093/eurheartj/ehn153.
MacDonald MR, Petrie MC, Varyani F, Ostergren J, Michelson EL, Young JB, Solomon SD, Granger CB, Swedberg K, Yusuf S, Pfeffer MA, McMurray JJV, CHARM Investigators. Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme. Eur Heart J. 2008 Jun;29(11):1377–1385.
Journal cover image

Published In

Eur Heart J

DOI

EISSN

1522-9645

Publication Date

June 2008

Volume

29

Issue

11

Start / End Page

1377 / 1385

Location

England

Related Subject Headings

  • Treatment Outcome
  • Tetrazoles
  • Stroke Volume
  • Prognosis
  • Male
  • Humans
  • Heart Failure
  • Female
  • Epidemiologic Methods
  • Diabetic Angiopathies