Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme.

Published

Journal Article

AIMS: To determine whether the risk of adverse cardiovascular (CV) outcomes associated with diabetes differs in patients with low and preserved ejection fraction (EF) heart failure (HF). METHODS AND RESULTS: We analysed outcomes in the Candesartan in Heart failure-Assessment of Reduction in Mortality and morbidity (CHARM) programme which randomized 7599 patients with symptomatic HF and a broad range of EF. The prevalence of diabetes was 28.3% in patients with preserved EF (>40%) and 28.5% in those with low EF (

Full Text

Duke Authors

Cited Authors

  • MacDonald, MR; Petrie, MC; Varyani, F; Ostergren, J; Michelson, EL; Young, JB; Solomon, SD; Granger, CB; Swedberg, K; Yusuf, S; Pfeffer, MA; McMurray, JJV; CHARM Investigators,

Published Date

  • June 2008

Published In

Volume / Issue

  • 29 / 11

Start / End Page

  • 1377 - 1385

PubMed ID

  • 18413309

Pubmed Central ID

  • 18413309

Electronic International Standard Serial Number (EISSN)

  • 1522-9645

Digital Object Identifier (DOI)

  • 10.1093/eurheartj/ehn153

Language

  • eng

Conference Location

  • England