Intracranial catheter for integrated 3D ultrasound imaging & hyperthermia: Feasibility study
Journal Article
In this study, we investigated the feasibility of an intracranial catheter transducer capable of real-time 3D (RT3D) imaging and ultrasound hyperthermia, for application in the visualization and treatment of tumors in the brain. We designed and constructed a 12 Fr, integrated matrix and linear array catheter transducer prototype for combined RT3D imaging and heating capability. This dual-mode catheter incorporated 153 matrix array elements and 11 linear array elements, on a 0.2 mm pitch, with a total aperture size of 8.4 mm × 2.3 mm. This array achieved a 3.5°C in vitro temperature rise at a 2 cm focal distance in tissue-mimicking material. The dual-mode catheter prototype was compared with a Siemens 10 Fr AcuNav™ catheter as a gold standard in experiments assessing image quality and therapeutic potential, and both probes were used in a canine brain model to image anatomical structures and color Doppler blood flow and to attempt in vivo heating. © 2009 American Institute of physics.
Full Text
Duke Authors
Cited Authors
- Herickhoff, CD; Light, ED; Bing, KF; Mukundan, S; Grant, GA; Wolf, PD; Dixon-Tulloch, E; Shih, T; Hsu, SJ; Smith, SW
Published Date
- July 21, 2009
Published In
Volume / Issue
- 1113 /
Start / End Page
- 342 - 346
Electronic International Standard Serial Number (EISSN)
- 1551-7616
International Standard Serial Number (ISSN)
- 0094-243X
Digital Object Identifier (DOI)
- 10.1063/1.3131444
Citation Source
- Scopus