The Holy Grail: long-acting local anaesthetics and liposomes.


Journal Article (Review)

The ability to provide an extended duration of analgesia of days following a single injection without the need for catheters, pumps and infusion systems would be a great benefit in acute and chronic pain. Exciting progress is being made in our ability to combine local anaesthetics with liposomes and polymer microspheres. These interesting formulations in animal models have allowed up to 4 days of analgesia. Their use clinically will be a great advance which could possibly occur in the near future.

Full Text

Cited Authors

  • Grant, SA

Published Date

  • June 2002

Published In

Volume / Issue

  • 16 / 2

Start / End Page

  • 345 - 352

PubMed ID

  • 12491562

Pubmed Central ID

  • 12491562

Electronic International Standard Serial Number (EISSN)

  • 1878-1608

International Standard Serial Number (ISSN)

  • 1521-6896

Digital Object Identifier (DOI)

  • 10.1053/bean.2002.0242


  • eng