A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products

Journal Article (Journal Article)

A new method for the synthesis of eight-membered heterocyclic 1,4,5-oxadiazocines has been described from β-diketone and β,β,β-triketone with an acidic α-hydrogen. The method entails the reaction of a di- or triketone with 2-hydroxyethylhydrazine and an aldehyde in the presence of acetic acid providing respectable yield. © 2005 Elsevier Ltd. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Liu, W; Guan, Z; Singh, SB

Published Date

  • November 14, 2005

Published In

Volume / Issue

  • 46 / 46

Start / End Page

  • 8009 - 8012

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/j.tetlet.2005.09.069

Citation Source

  • Scopus