Solvation of acylium fragment ions in electrospray ionization quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry.

Published

Journal Article

In electrospray ionization (ESI) quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry, certain fragment ions (e.g. acylium ions) generated either during the ion transportation process (in the source interface region) or in the ion trap are found to undergo ion--molecule reactions with ESI solvent molecules (water, acetonitrile and aliphatic alcohols) to form adduct species. These unexpected solvated fragment ions severely complicate the interpretation of mass spectrometic data. High-resolution accurate mass measurements are important in establishing the elemental compositions of these adduct species and preventing erroneous data interpretation.

Full Text

Duke Authors

Cited Authors

  • Guan, Z; Liesch, JM

Published Date

  • March 2001

Published In

Volume / Issue

  • 36 / 3

Start / End Page

  • 264 - 276

PubMed ID

  • 11312518

Pubmed Central ID

  • 11312518

Electronic International Standard Serial Number (EISSN)

  • 1096-9888

International Standard Serial Number (ISSN)

  • 1076-5174

Digital Object Identifier (DOI)

  • 10.1002/jms.124

Language

  • eng