Engineered cartilage using primary chondrocytes cultured in a porous cartilage-derived matrix.

Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't

To investigate the cell growth, matrix accumulation and mechanical properties of neocartilage formed by human or porcine articular chondrocytes on a porous, porcine cartilage-derived matrix (CDM) for use in cartilage tissue engineering. MATERIALS & Methods: We examined the physical properties, cell infiltration and matrix accumulation in different formulations of CDM and selected a CDM made of homogenized cartilage slurry as an appropriate scaffold for long-term culture of human and porcine articular chondrocytes.

Full Text

Duke Authors

Cited Authors

  • Cheng, NC; Estes, BT; Young, TH; Guilak, F

Published Date

  • January 2011

Published In

Volume / Issue

  • 6 / 1

Start / End Page

  • 81 - 93

PubMed ID

  • 21175289

Electronic International Standard Serial Number (EISSN)

  • 1746-076X

Digital Object Identifier (DOI)

  • 10.2217/rme.10.87

Language

  • eng

Citation Source

  • PubMed