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In vitro Differentiation Potential of Mesenchymal Stem Cells.

Publication ,  Journal Article
Gimble, JM; Guilak, F; Nuttall, ME; Sathishkumar, S; Vidal, M; Bunnell, BA
Published in: Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie
January 2008

SUMMARY: Mesenchymal stem cells (MSCs) represent a class of multipotent progenitor cells that have been isolated from multiple tissue sites. Of these, adipose tissue and bone marrow offer advantages in terms of access, abundance, and the extent of their documentation in the literature. This review focuses on the in vitro differentiation capability of cells derived from adult human tissue. Multiple, independent studies have demonstrated that MSCs can commit to mesodermal (adipocyte, chondrocyte, hematopoietic support, myocyte, osteoblast, tenocyte), ectodermal (epithelial, glial, neural), and endodermal (hepatocyte, islet cell) lineages. The limitations and promises of these studies in the context of tissue engineering are discussed.

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Published In

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

DOI

EISSN

1660-3818

ISSN

1660-3796

Publication Date

January 2008

Volume

35

Issue

3

Start / End Page

228 / 238

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

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Gimble, J. M., Guilak, F., Nuttall, M. E., Sathishkumar, S., Vidal, M., & Bunnell, B. A. (2008). In vitro Differentiation Potential of Mesenchymal Stem Cells. Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie, 35(3), 228–238. https://doi.org/10.1159/000124281
Gimble, Jeffrey M., Farshid Guilak, Mark E. Nuttall, Solomon Sathishkumar, Martin Vidal, and Bruce A. Bunnell. “In vitro Differentiation Potential of Mesenchymal Stem Cells.Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie 35, no. 3 (January 2008): 228–38. https://doi.org/10.1159/000124281.
Gimble JM, Guilak F, Nuttall ME, Sathishkumar S, Vidal M, Bunnell BA. In vitro Differentiation Potential of Mesenchymal Stem Cells. Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie. 2008 Jan;35(3):228–38.
Gimble, Jeffrey M., et al. “In vitro Differentiation Potential of Mesenchymal Stem Cells.Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie, vol. 35, no. 3, Jan. 2008, pp. 228–38. Epmc, doi:10.1159/000124281.
Gimble JM, Guilak F, Nuttall ME, Sathishkumar S, Vidal M, Bunnell BA. In vitro Differentiation Potential of Mesenchymal Stem Cells. Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie. 2008 Jan;35(3):228–238.
Journal cover image

Published In

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

DOI

EISSN

1660-3818

ISSN

1660-3796

Publication Date

January 2008

Volume

35

Issue

3

Start / End Page

228 / 238

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences