Circadian oscillation of gene expression in murine calvarial bone.

Comparative Study, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't

The genes encoding the core circadian transcription factors display an oscillating expression profile in murine calvarial bone. More than 26% of the calvarial bone transcriptome exhibits a circadian rhythm, comparable with that observed in brown and white adipose tissues and liver. Thus, circadian mechanisms may directly modulate oxidative phosphorylation and multiple metabolic pathways in bone homeostasis.

Full Text

Duke Authors

Cited Authors

  • Zvonic, S; Ptitsyn, AA; Kilroy, G; Wu, X; Conrad, SA; Scott, LK; Guilak, F; Pelled, G; Gazit, D; Gimble, JM

Published Date

  • March 2007

Published In

Volume / Issue

  • 22 / 3

Start / End Page

  • 357 - 365

PubMed ID

  • 17144790

International Standard Serial Number (ISSN)

  • 0884-0431

Digital Object Identifier (DOI)

  • 10.1359/jbmr.061114


  • eng

Citation Source

  • PubMed