Circadian oscillation of gene expression in murine calvarial bone.
Comparative Study, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
The genes encoding the core circadian transcription factors display an oscillating expression profile in murine calvarial bone. More than 26% of the calvarial bone transcriptome exhibits a circadian rhythm, comparable with that observed in brown and white adipose tissues and liver. Thus, circadian mechanisms may directly modulate oxidative phosphorylation and multiple metabolic pathways in bone homeostasis.
Zvonic, S; Ptitsyn, AA; Kilroy, G; Wu, X; Conrad, SA; Scott, LK; Guilak, F; Pelled, G; Gazit, D; Gimble, JM
Volume / Issue
Start / End Page
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)