The arterial wall and the atherosclerotic lesion.
Journal Article (Journal Article;Review)
The role of the lipid-rich core region in atherogenesis is beginning to be understood, from its inception in early lesions to its catastrophic effects in promoting plaque rupture in late lesions. Besides the lipid-rich core, recent studies on human and animal atherosclerosis have drawn attention to atherogenic lipoproteins larger than LDL, unesterified cholesterol in lesions, apolipoprotein E as an antiatherogenic factor, macrophages as atherogenic effector cells, and unexpectedly slow rates of smooth muscle cell proliferation.
Full Text
Duke Authors
Cited Authors
- Guyton, JR
Published Date
- October 1994
Published In
Volume / Issue
- 5 / 5
Start / End Page
- 376 - 381
PubMed ID
- 7858913
International Standard Serial Number (ISSN)
- 0957-9672
Digital Object Identifier (DOI)
- 10.1097/00041433-199410000-00010
Language
- eng
Conference Location
- England