The development of an implantable electrochemical glucose sensor: response to glucose in bovine serum ultrafiltrate.

Journal Article (Journal Article)

A glucose sensor based on organic oxidation reactions at a platinum electrode is being developed as the key component for an implantable artificial beta cell for diabetic patients. Sensitivity of a membrane-covered platinum electrode to changing glucose concentration in bovine serum ultrafiltrate has been demonstrated, with current response as high as 60 microamperes per 100 mg/dl change in glucose concentration. Reproducibility of measurements probably will depend on satisfactory mechanical assembly of the membrane-electrode combination. An approach to selectivity based on multiple current measurements is suggested.

Full Text

Duke Authors

Cited Authors

  • Guyton, JR; Soeldner, JS; Giner, J; Colton, CK; Morris, RS

Published Date

  • 1979

Published In

Start / End Page

  • 24 - 26

PubMed ID

  • 395084

International Standard Serial Number (ISSN)

  • 0170-5903


  • eng

Conference Location

  • Germany