Skip to main content
Journal cover image

Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids.

Publication ,  Journal Article
Olofsson, LE; Olsson, B; Lystig, T; Jacobson, P; Jernås, M; Sjöholm, K; Gummesson, A; Sjöström, L; Eriksson, P; Hamsten, A; Hale, LP ...
Published in: Metabolism
September 2010

Zn-alpha2-glycoprotein (ZAG) is a serum protein implicated in cancer cachexia and lipolysis. Our aim was to investigate serum levels of ZAG and polymorphisms in the ZAG gene in relation to serum lipids in man. Serum levels of ZAG correlated with serum levels of cholesterol (P = .00088) in healthy subjects and during weight loss (P = .059). The ZAG genotype was associated with total cholesterol (P = .014) and low-density lipoprotein cholesterol (P = .026) in healthy subjects, and the associations were replicated in an additional cohort (P = .0017 and P = .060, respectively). Our data indicate that ZAG plays a role in lipid metabolism.

Duke Scholars

Published In

Metabolism

DOI

EISSN

1532-8600

Publication Date

September 2010

Volume

59

Issue

9

Start / End Page

1316 / 1318

Location

United States

Related Subject Headings

  • Zn-Alpha-2-Glycoprotein
  • Seminal Plasma Proteins
  • Polymorphism, Genetic
  • Male
  • Lipids
  • Immunoassay
  • Humans
  • Genotype
  • Genetic Association Studies
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Olofsson, L. E., Olsson, B., Lystig, T., Jacobson, P., Jernås, M., Sjöholm, K., … Carlsson, L. M. S. (2010). Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids. Metabolism, 59(9), 1316–1318. https://doi.org/10.1016/j.metabol.2009.12.006
Olofsson, Louise E., Bob Olsson, Theodore Lystig, Peter Jacobson, Margareta Jernås, Kajsa Sjöholm, Anders Gummesson, et al. “Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids.Metabolism 59, no. 9 (September 2010): 1316–18. https://doi.org/10.1016/j.metabol.2009.12.006.
Olofsson LE, Olsson B, Lystig T, Jacobson P, Jernås M, Sjöholm K, et al. Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids. Metabolism. 2010 Sep;59(9):1316–8.
Olofsson, Louise E., et al. “Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids.Metabolism, vol. 59, no. 9, Sept. 2010, pp. 1316–18. Pubmed, doi:10.1016/j.metabol.2009.12.006.
Olofsson LE, Olsson B, Lystig T, Jacobson P, Jernås M, Sjöholm K, Gummesson A, Sjöström L, Eriksson P, Hamsten A, Hale LP, Thelle DS, Carlsson B, Carlsson LMS. Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids. Metabolism. 2010 Sep;59(9):1316–1318.
Journal cover image

Published In

Metabolism

DOI

EISSN

1532-8600

Publication Date

September 2010

Volume

59

Issue

9

Start / End Page

1316 / 1318

Location

United States

Related Subject Headings

  • Zn-Alpha-2-Glycoprotein
  • Seminal Plasma Proteins
  • Polymorphism, Genetic
  • Male
  • Lipids
  • Immunoassay
  • Humans
  • Genotype
  • Genetic Association Studies
  • Female