Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts.

Journal Article (Journal Article)

Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.

Full Text

Duke Authors

Cited Authors

  • Murrell, DF; Daniel, BS; Joly, P; Borradori, L; Amagai, M; Hashimoto, T; Caux, F; Marinovic, B; Sinha, AA; Hertl, M; Bernard, P; Sirois, D; Cianchini, G; Fairley, JA; Jonkman, MF; Pandya, AG; Rubenstein, D; Zillikens, D; Payne, AS; Woodley, D; Zambruno, G; Aoki, V; Pincelli, C; Diaz, L; Hall, RP; Meurer, M; Mascaro, JM; Schmidt, E; Shimizu, H; Zone, J; Swerlick, R; Mimouni, D; Culton, D; Lipozencic, J; Bince, B; Grando, SA; Bystryn, J-C; Werth, VP

Published Date

  • March 2012

Published In

Volume / Issue

  • 66 / 3

Start / End Page

  • 479 - 485

PubMed ID

  • 22056920

Pubmed Central ID

  • 22056920

Electronic International Standard Serial Number (EISSN)

  • 1097-6787

Digital Object Identifier (DOI)

  • 10.1016/j.jaad.2011.06.032


  • eng

Conference Location

  • United States