Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus.

Journal Article (Journal Article)

Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.

Full Text

Duke Authors

Cited Authors

  • Murrell, DF; Dick, S; Ahmed, AR; Amagai, M; Barnadas, MA; Borradori, L; Bystryn, J-C; Cianchini, G; Diaz, L; Fivenson, D; Hall, R; Harman, KE; Hashimoto, T; Hertl, M; Hunzelmann, N; Iranzo, P; Joly, P; Jonkman, MF; Kitajima, Y; Korman, NJ; Martin, LK; Mimouni, D; Pandya, AG; Payne, AS; Rubenstein, D; Shimizu, H; Sinha, AA; Sirois, D; Zillikens, D; Werth, VP

Published Date

  • June 2008

Published In

Volume / Issue

  • 58 / 6

Start / End Page

  • 1043 - 1046

PubMed ID

  • 18339444

Pubmed Central ID

  • 18339444

Electronic International Standard Serial Number (EISSN)

  • 1097-6787

Digital Object Identifier (DOI)

  • 10.1016/j.jaad.2008.01.012


  • eng

Conference Location

  • United States