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The normal organization of the lateral posterior nucleus of the golden hamster.

Publication ,  Journal Article
Crain, BJ; Hall, WC
Published in: J Comp Neurol
September 15, 1980

As a first step in analyzing the influence of various afferent projections on the development of the hamster lateral posterior nucleus, its normal organization was studied using both light and electron microscopic techniques. Rostrolateral, rostromedial, and caudal subdivisions were identified. The rostrolateral subdivision receives dense projections from the ipsilateral superior colliculus and posterior neocortex, as well as sparser, more restricted projections from the contralateral colliculus and retina. The ipsilateral colliculus is by far the major source of medium-sized (M)terminals with round vesicles. These terminals synapse around the shafts of large central dendrites to form distinctive synaptic clusters. The contralateral colliculus and retina contribute a few M-terminals to the clusters. In contrast, axons from the posterior neocortex form very large (RL-)terminals with round vesicles from the posterior neocortex form very large (RL)terminals with round vesicles which synapse onto numerous appendages of single proximal dendrite, are surrounded by glial lamellae, and rarely participate in the clusters. Axons from all four sources also form small (RS)terminals with round vesicles which synapse on the shafts of small dendrites. Finally, F-terminals with flat or pleomorphic vesicles form symmetric synaptic contacts both within and outside the clusters. The only identified projection to the rostromedial subdivision is from the ipsilateral posterior neocortex, which contributes RL- and RS-terminals. F-terminals are also found, but neither M-terminals nor synaptic clusters are present. The caudal subdivision also receives RL- and RS-terminals from the ipsilateral posterior neocortex. Small inputs from the ipsilateral and contralateral colliculi are present, but their axons form only RS-terminals. No M-terminals or synaptic clusters are found. These results indicate that a large neonatal superior colliculus lesion would eliminate the vast majority of the M-terminals in the synaptic clusters of the ipsilateral lateral posterior nucleus. In subsequent studies (Crain and Hall, '80 a,b,c), we will examine how the remaining inputs from the retina, contralateral superior colliculus, and posterior neocortex contribute to the synaptic organization when it develops after such a lesion.

Duke Scholars

Published In

J Comp Neurol

DOI

ISSN

0021-9967

Publication Date

September 15, 1980

Volume

193

Issue

2

Start / End Page

351 / 370

Location

United States

Related Subject Headings

  • Visual Pathways
  • Visual Cortex
  • Synapses
  • Superior Colliculi
  • Retina
  • Neurons
  • Neurology & Neurosurgery
  • Microscopy, Electron
  • Mesocricetus
  • Geniculate Bodies
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Crain, B. J., & Hall, W. C. (1980). The normal organization of the lateral posterior nucleus of the golden hamster. J Comp Neurol, 193(2), 351–370. https://doi.org/10.1002/cne.901930204
Crain, B. J., and W. C. Hall. “The normal organization of the lateral posterior nucleus of the golden hamster.J Comp Neurol 193, no. 2 (September 15, 1980): 351–70. https://doi.org/10.1002/cne.901930204.
Crain BJ, Hall WC. The normal organization of the lateral posterior nucleus of the golden hamster. J Comp Neurol. 1980 Sep 15;193(2):351–70.
Crain, B. J., and W. C. Hall. “The normal organization of the lateral posterior nucleus of the golden hamster.J Comp Neurol, vol. 193, no. 2, Sept. 1980, pp. 351–70. Pubmed, doi:10.1002/cne.901930204.
Crain BJ, Hall WC. The normal organization of the lateral posterior nucleus of the golden hamster. J Comp Neurol. 1980 Sep 15;193(2):351–370.
Journal cover image

Published In

J Comp Neurol

DOI

ISSN

0021-9967

Publication Date

September 15, 1980

Volume

193

Issue

2

Start / End Page

351 / 370

Location

United States

Related Subject Headings

  • Visual Pathways
  • Visual Cortex
  • Synapses
  • Superior Colliculi
  • Retina
  • Neurons
  • Neurology & Neurosurgery
  • Microscopy, Electron
  • Mesocricetus
  • Geniculate Bodies