Clinical application of PET for the evaluation of brain tumors.

Journal Article (Review)

The combination of FDG and PET has demonstrated clinical utility in the evaluation of patients with brain tumors. At the time of diagnosis, FDG PET provides information concerning the degree of malignancy and patient prognosis. After therapy, FDG PET is able to assess persistence of tumor, determine degree of malignancy, monitor progression, differentiate recurrence from necrosis, and assess prognosis. Other studies using PET provide information that may be clinically useful. Determination of tumor blood flow and permeability of the blood-brain barrier may help in the selection of appropriate therapy. Amino acid imaging using 11C-methionine is being evaluated in patients with brain tumors and provides different information than FDG imaging.

Full Text

Duke Authors

Cited Authors

  • Coleman, RE; Hoffman, JM; Hanson, MW; Sostman, HD; Schold, SC

Published Date

  • April 1991

Published In

Volume / Issue

  • 32 / 4

Start / End Page

  • 616 - 622

PubMed ID

  • 2013802

Pubmed Central ID

  • 2013802

International Standard Serial Number (ISSN)

  • 0161-5505


  • eng

Conference Location

  • United States