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Carcinoid tumors: iodine-131 MIBG scintigraphy.

Publication ,  Journal Article
Hanson, MW; Feldman, JM; Blinder, RA; Moore, JO; Coleman, RE
Published in: Radiology
September 1989

Eighty-two patients with pathologically proved carcinoid tumors were examined with iodine-131 metaio-dobenzylguanidine (MIBG) scintigraphy. Localization scores of I-131 MIBG accumulation in the primary tumor or metastatic site ranged from 0 to 3+ on the basis of comparison with normal liver. I-131 MIBG uptake varied greatly in different patients with carcinoid tumors. The localization scores in known tumor sites were related to the location of the primary tumor in the stomach (1-3+ in two of five patients), pancreas (1-3+ in four of five patients), cecum (3+ in two of two patients), appendix (0 in one of one patient), jejunum (0 in one of one patient), Meckel diverticulum (3+ in one of one patient), terminal ileum (2-3+ in 19 of 28 patients), bronchus (3+ in one of nine patients), thymus (1+ in one of two patients), and unknown (2-3+ in 18 of 28 patients). Tumors of midgut origin concentrated I-131 MIBG more frequently than those of foregut origin. Uptake of I-131 MIBG was more likely if neurohumor levels, particularly serum serotonin, were elevated. There was no relationship of I-131 MIBG uptake to carcinoid syndrome. I-131 MIBG is useful in the determination of the location and extent of some carcinoid tumors, particularly those of midgut origin.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

September 1989

Volume

172

Issue

3

Start / End Page

699 / 703

Location

United States

Related Subject Headings

  • Radionuclide Imaging
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Iodobenzenes
  • Iodine Radioisotopes
  • Ileal Neoplasms
  • Humans
  • Female
  • Contrast Media
 

Citation

APA
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Hanson, M. W., Feldman, J. M., Blinder, R. A., Moore, J. O., & Coleman, R. E. (1989). Carcinoid tumors: iodine-131 MIBG scintigraphy. Radiology, 172(3), 699–703. https://doi.org/10.1148/radiology.172.3.2772175
Hanson, M. W., J. M. Feldman, R. A. Blinder, J. O. Moore, and R. E. Coleman. “Carcinoid tumors: iodine-131 MIBG scintigraphy.Radiology 172, no. 3 (September 1989): 699–703. https://doi.org/10.1148/radiology.172.3.2772175.
Hanson MW, Feldman JM, Blinder RA, Moore JO, Coleman RE. Carcinoid tumors: iodine-131 MIBG scintigraphy. Radiology. 1989 Sep;172(3):699–703.
Hanson, M. W., et al. “Carcinoid tumors: iodine-131 MIBG scintigraphy.Radiology, vol. 172, no. 3, Sept. 1989, pp. 699–703. Pubmed, doi:10.1148/radiology.172.3.2772175.
Hanson MW, Feldman JM, Blinder RA, Moore JO, Coleman RE. Carcinoid tumors: iodine-131 MIBG scintigraphy. Radiology. 1989 Sep;172(3):699–703.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

September 1989

Volume

172

Issue

3

Start / End Page

699 / 703

Location

United States

Related Subject Headings

  • Radionuclide Imaging
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Iodobenzenes
  • Iodine Radioisotopes
  • Ileal Neoplasms
  • Humans
  • Female
  • Contrast Media