Tests for 2 × 2 tables in clinical trials

Journal Article

Five standard tests are compared: chi-squared, Fisher's exact, Yates' correction, Fisher's exact mid-p, and Barnard's. Yates' is always inferior to Fisher's exact. Fisher's exact is so conservative that one should look for alternatives. For certain sample sizes, Fisher's mid-p or Barnard's test maintain the nominal alpha and have superior power. Copyright © 2007 JMASM, Inc.

Full Text

Duke Authors

Cited Authors

  • Hasselblad, V; Lokhnygina, Y

Published Date

  • January 1, 2007

Published In

Volume / Issue

  • 6 / 2

Start / End Page

  • 456 - 468

Electronic International Standard Serial Number (EISSN)

  • 1538-9472

International Standard Serial Number (ISSN)

  • 1538-9472

Digital Object Identifier (DOI)

  • 10.22237/jmasm/1193890140

Citation Source

  • Scopus