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Prevalence of neuropsychiatric symptoms in CIND and its subtypes: the Cache County Study.

Publication ,  Journal Article
Peters, ME; Rosenberg, PB; Steinberg, M; Tschanz, JT; Norton, MC; Welsh-Bohmer, KA; Hayden, KM; Breitner, JCS; Lyketsos, CG ...
Published in: Am J Geriatr Psychiatry
May 2012

OBJECTIVES: 1) To report rates of neuropsychiatric symptoms (NPS) in cognitive impairment, no dementia (CIND). 2) To compare the 30-day prevalence of NPS in CIND with that in dementia and cognitively normal individuals. 3) To compare the prevalence of NPS in amnestic MCI (aMCI) with other predementia syndromes. DESIGN: Comparison of prevalence proportions among several defined groups. SETTING: Population-based study. PARTICIPANTS: A subsample of the permanent residents of Cache County, Utah, aged 65 years or older in January 1995 (N = 5092) and who had completed clinical assessments and had an informant-completed Neuropsychiatric Inventory. MEASUREMENTS: Chi-square statistics, tests for trend, and logistic regression models were used to analyze the three objectives listed earlier. RESULTS: The most prevalent NPS in those with CIND were depression (16.9%), irritability (9.8%), nighttime behaviors (7.6%), apathy (6.9%), and anxiety (5.4%). Trend analyses confirmed that the CIND group had NPS prevalence rates that fell between the normal and dementia groups for most NPS. Logistic regression models showed no significant difference between aMCI and other CIND participants in the prevalence of any NPS (lowest p: 0.316). CONCLUSIONS: These data confirm the relatively high prevalence of NPS in CIND reported by other studies, especially for affective symptoms. No differences in NPS prevalence were found between aMCI and other types of CIND.

Duke Scholars

Published In

Am J Geriatr Psychiatry

DOI

EISSN

1545-7214

Publication Date

May 2012

Volume

20

Issue

5

Start / End Page

416 / 424

Location

England

Related Subject Headings

  • Utah
  • Neuropsychological Tests
  • Mental Disorders
  • Male
  • Irritable Mood
  • Humans
  • Geriatrics
  • Female
  • Depression
  • Dementia
 

Citation

APA
Chicago
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MLA
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Peters, M. E., Rosenberg, P. B., Steinberg, M., Tschanz, J. T., Norton, M. C., Welsh-Bohmer, K. A., … Cache County Investigators, . (2012). Prevalence of neuropsychiatric symptoms in CIND and its subtypes: the Cache County Study. Am J Geriatr Psychiatry, 20(5), 416–424. https://doi.org/10.1097/JGP.0b013e318211057d
Peters, Matthew E., Paul B. Rosenberg, Martin Steinberg, JoAnn T. Tschanz, Maria C. Norton, Kathleen A. Welsh-Bohmer, Kathleen M. Hayden, John C. S. Breitner, Constantine G. Lyketsos, and Constantine G. Cache County Investigators. “Prevalence of neuropsychiatric symptoms in CIND and its subtypes: the Cache County Study.Am J Geriatr Psychiatry 20, no. 5 (May 2012): 416–24. https://doi.org/10.1097/JGP.0b013e318211057d.
Peters ME, Rosenberg PB, Steinberg M, Tschanz JT, Norton MC, Welsh-Bohmer KA, et al. Prevalence of neuropsychiatric symptoms in CIND and its subtypes: the Cache County Study. Am J Geriatr Psychiatry. 2012 May;20(5):416–24.
Peters, Matthew E., et al. “Prevalence of neuropsychiatric symptoms in CIND and its subtypes: the Cache County Study.Am J Geriatr Psychiatry, vol. 20, no. 5, May 2012, pp. 416–24. Pubmed, doi:10.1097/JGP.0b013e318211057d.
Peters ME, Rosenberg PB, Steinberg M, Tschanz JT, Norton MC, Welsh-Bohmer KA, Hayden KM, Breitner JCS, Lyketsos CG, Cache County Investigators. Prevalence of neuropsychiatric symptoms in CIND and its subtypes: the Cache County Study. Am J Geriatr Psychiatry. 2012 May;20(5):416–424.
Journal cover image

Published In

Am J Geriatr Psychiatry

DOI

EISSN

1545-7214

Publication Date

May 2012

Volume

20

Issue

5

Start / End Page

416 / 424

Location

England

Related Subject Headings

  • Utah
  • Neuropsychological Tests
  • Mental Disorders
  • Male
  • Irritable Mood
  • Humans
  • Geriatrics
  • Female
  • Depression
  • Dementia