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Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques

Publication ,  Journal Article
Perry, NB; Ellis, G; Blunt, JW; Haystead, TAJ; Lake, RJ; Munro, MHG
Published in: Natural Product Letters
January 1, 1998

Using a combination of P388 cytotoxicity testing, protein phosphatase enzyme inhibition assays and an ELISA immunoassay, okadaic acid, the causative agent of diarrhetic shellfish poisoning (DSP), has been found in Raspalia agminata, and detected in two other species of New Zealand sponges.

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Published In

Natural Product Letters

DOI

ISSN

1057-5634

Publication Date

January 1, 1998

Volume

11

Issue

4

Start / End Page

305 / 312

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
 

Citation

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Perry, N. B., Ellis, G., Blunt, J. W., Haystead, T. A. J., Lake, R. J., & Munro, M. H. G. (1998). Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques. Natural Product Letters, 11(4), 305–312. https://doi.org/10.1080/10575639808044964
Perry, N. B., G. Ellis, J. W. Blunt, T. A. J. Haystead, R. J. Lake, and M. H. G. Munro. “Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques.” Natural Product Letters 11, no. 4 (January 1, 1998): 305–12. https://doi.org/10.1080/10575639808044964.
Perry NB, Ellis G, Blunt JW, Haystead TAJ, Lake RJ, Munro MHG. Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques. Natural Product Letters. 1998 Jan 1;11(4):305–12.
Perry, N. B., et al. “Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques.” Natural Product Letters, vol. 11, no. 4, Jan. 1998, pp. 305–12. Scopus, doi:10.1080/10575639808044964.
Perry NB, Ellis G, Blunt JW, Haystead TAJ, Lake RJ, Munro MHG. Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques. Natural Product Letters. 1998 Jan 1;11(4):305–312.

Published In

Natural Product Letters

DOI

ISSN

1057-5634

Publication Date

January 1, 1998

Volume

11

Issue

4

Start / End Page

305 / 312

Related Subject Headings

  • Medicinal & Biomolecular Chemistry