Potential use of BacT/Alert automated blood culture system for antifungal susceptibility testing.


Journal Article

A simple, rapid susceptibility test is needed to determine the possible resistance of yeasts to commonly used antifungal agents. The BacT/Alert automated blood culture system was evaluated as one technology for development of such a test. Yeast nitrogen base was used as the growth medium, and amphotericin B was the test antifungal agent. Isolates of various Candida species, Torulopsis glabrata, Saccharomyces cerevisiae, and Cryptococcus neoformans were evaluated. The results suggest that detection of amphotericin B resistance of yeast isolates within 12 to 14 h after inoculation of test medium is possible.

Full Text

Cited Authors

  • Hazen, KC; Chery, MP; Han, Y

Published Date

  • March 1994

Published In

Volume / Issue

  • 32 / 3

Start / End Page

  • 848 - 850

PubMed ID

  • 8195407

Pubmed Central ID

  • 8195407

Electronic International Standard Serial Number (EISSN)

  • 1098-660X

International Standard Serial Number (ISSN)

  • 0095-1137

Digital Object Identifier (DOI)

  • 10.1128/jcm.32.3.848-850.1994


  • eng