Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals.

Journal Article (Review)

Infectious fungi are among a broad group of microbial pathogens that has and continues to emerge concomitantly due to the global AIDS pandemic as well as an overall increase of patients with compromised immune systems. In addition, many pathogens have been emerging and re-emerging, causing disease in both individuals who have an identifiable immune defect and those who do not. The fungal pathogen Cryptococcus gattii can infect individuals with and without an identifiable immune defect, with a broad geographic range including both endemic areas and emerging outbreak regions. Infections in patients and animals can be severe and often fatal if untreated. We review the molecular epidemiology, population structure, clinical manifestations, and ecological niche of this emerging pathogen.

Full Text

Duke Authors

Cited Authors

  • Byrnes, EJ; Bartlett, KH; Perfect, JR; Heitman, J

Published Date

  • October 2011

Published In

Volume / Issue

  • 13 / 11

Start / End Page

  • 895 - 907

PubMed ID

  • 21684347

Electronic International Standard Serial Number (EISSN)

  • 1769-714X

Digital Object Identifier (DOI)

  • 10.1016/j.micinf.2011.05.009

Language

  • eng

Conference Location

  • France