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Orchestration of sexual reproduction and virulence by the fungal mating-type locus.

Publication ,  Journal Article
Hsueh, Y-P; Heitman, J
Published in: Curr Opin Microbiol
December 2008

The mating-type locus (MAT) orchestrates sexual reproduction in fungi. Sexual reproduction is related not only to fitness of an organism, but also correlated with virulence in certain pathogens. In the dandruff-associated fungus Malassesia globosa, although the sexual cycle remains to be discovered, whole genome analysis has led to the hypothesis that mating may occur on host skin. Furthermore, the MAT locus of M. globosa and U. hordei provides evidence that transitions between tetrapolar and bipolar systems have independently occurred. These results, together with studies recapitulating the ancestral tetrapolar mating system in Cryptococcus and the structure of MAT in related smut fungi, have furthered understanding on transitions between different mating systems and the evolution of MAT in the Basidiomycota.

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Published In

Curr Opin Microbiol

DOI

EISSN

1879-0364

Publication Date

December 2008

Volume

11

Issue

6

Start / End Page

517 / 524

Location

England

Related Subject Headings

  • Virulence
  • Recombination, Genetic
  • Microbiology
  • Humans
  • Genes, Mating Type, Fungal
  • Basidiomycota
  • Animals
  • Adaptation, Biological
  • 3107 Microbiology
  • 1108 Medical Microbiology
 

Citation

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ICMJE
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Hsueh, Y.-P., & Heitman, J. (2008). Orchestration of sexual reproduction and virulence by the fungal mating-type locus. Curr Opin Microbiol, 11(6), 517–524. https://doi.org/10.1016/j.mib.2008.09.014
Hsueh, Yen-Ping, and Joseph Heitman. “Orchestration of sexual reproduction and virulence by the fungal mating-type locus.Curr Opin Microbiol 11, no. 6 (December 2008): 517–24. https://doi.org/10.1016/j.mib.2008.09.014.
Hsueh Y-P, Heitman J. Orchestration of sexual reproduction and virulence by the fungal mating-type locus. Curr Opin Microbiol. 2008 Dec;11(6):517–24.
Hsueh, Yen-Ping, and Joseph Heitman. “Orchestration of sexual reproduction and virulence by the fungal mating-type locus.Curr Opin Microbiol, vol. 11, no. 6, Dec. 2008, pp. 517–24. Pubmed, doi:10.1016/j.mib.2008.09.014.
Hsueh Y-P, Heitman J. Orchestration of sexual reproduction and virulence by the fungal mating-type locus. Curr Opin Microbiol. 2008 Dec;11(6):517–524.
Journal cover image

Published In

Curr Opin Microbiol

DOI

EISSN

1879-0364

Publication Date

December 2008

Volume

11

Issue

6

Start / End Page

517 / 524

Location

England

Related Subject Headings

  • Virulence
  • Recombination, Genetic
  • Microbiology
  • Humans
  • Genes, Mating Type, Fungal
  • Basidiomycota
  • Animals
  • Adaptation, Biological
  • 3107 Microbiology
  • 1108 Medical Microbiology