A Model of 3D Propagation in Discrete Cardiac Tissue.

Journal Article (Journal Article)

A model was developed of a bundle of cardiac fibers embedded in an extracellular space. In contrast to the classical bidomain approach, the model is constructed such that the intracellular and extracellular spaces are spatially distinct. The model was used to test the hypothesis that the distribution of the extracellular fluid in the tissue can affect the conduction velocity. The preliminary results suggest that under nominally normal conditions, the propagation speed depends on the fraction of extracellular space and less on the actual distribution of extracellular space within the bundle.

Full Text

Duke Authors

Cited Authors

  • Stinstra, J; Roberts, S; Pormann, J; Macleod, R; Henriquez, C

Published Date

  • January 2006

Published In

Volume / Issue

  • 33 /

Start / End Page

  • 41 - 44

PubMed ID

  • 17404606

Pubmed Central ID

  • PMC1847422

International Standard Serial Number (ISSN)

  • 0276-6574

Language

  • eng