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Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee.

Publication ,  Journal Article
Stevenson, WG; Hernandez, AF; Carson, PE; Fang, JC; Katz, SD; Spertus, JA; Sweitzer, NK; Tang, WHW; Albert, NM; Butler, J; Westlake Canary, CA ...
Published in: J Card Fail
February 2012

Cardiac resynchronization therapy (CRT) improves survival, symptoms, quality of life, exercise capacity, and cardiac structure and function in patients with New York Heart Association (NYHA) functional class II or ambulatory class IV heart failure (HF) with wide QRS complex. The totality of evidence supports the use of CRT in patients with less severe HF symptoms. CRT is recommended for patients in sinus rhythm with a widened QRS interval (≥150 ms) not due to right bundle branch block (RBBB) who have severe left ventricular (LV) systolic dysfunction and persistent NYHA functional class II-III symptoms despite optimal medical therapy (strength of evidence A). CRT may be considered for several other patient groups for whom evidence of benefit is clinically significant but less substantial, including patients with a QRS interval of ≥120 to <150 ms and severe LV systolic dysfunction who have persistent mild to severe HF despite optimal medical therapy (strength of evidence B), some patients with atrial fibrillation, and some with ambulatory class IV HF. Several evidence gaps remain that need to be addressed, including the ideal threshold for QRS duration, QRS morphology, lead placement, degree of myocardial scarring, and the modality for evaluating dyssynchrony. Recommendations will evolve over time as additional data emerge from completed and ongoing clinical trials.

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Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

February 2012

Volume

18

Issue

2

Start / End Page

94 / 106

Location

United States

Related Subject Headings

  • United States
  • Societies, Medical
  • Humans
  • Heart Failure
  • Cardiovascular System & Hematology
  • Cardiology
  • Cardiac Resynchronization Therapy
  • Cardiac Pacing, Artificial
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

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Stevenson, W. G., Hernandez, A. F., Carson, P. E., Fang, J. C., Katz, S. D., Spertus, J. A., … Heart Failure Society of America Guideline Committee, . (2012). Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee. J Card Fail, 18(2), 94–106. https://doi.org/10.1016/j.cardfail.2011.12.004
Stevenson, William G., Adrian F. Hernandez, Peter E. Carson, James C. Fang, Stuart D. Katz, John A. Spertus, Nancy K. Sweitzer, et al. “Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee.J Card Fail 18, no. 2 (February 2012): 94–106. https://doi.org/10.1016/j.cardfail.2011.12.004.
Stevenson WG, Hernandez AF, Carson PE, Fang JC, Katz SD, Spertus JA, et al. Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee. J Card Fail. 2012 Feb;18(2):94–106.
Stevenson, William G., et al. “Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee.J Card Fail, vol. 18, no. 2, Feb. 2012, pp. 94–106. Pubmed, doi:10.1016/j.cardfail.2011.12.004.
Stevenson WG, Hernandez AF, Carson PE, Fang JC, Katz SD, Spertus JA, Sweitzer NK, Tang WHW, Albert NM, Butler J, Westlake Canary CA, Collins SP, Colvin-Adams M, Ezekowitz JA, Givertz MM, Hershberger RE, Rogers JG, Teerlink JR, Walsh MN, Stough WG, Starling RC, Heart Failure Society of America Guideline Committee. Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee. J Card Fail. 2012 Feb;18(2):94–106.
Journal cover image

Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

February 2012

Volume

18

Issue

2

Start / End Page

94 / 106

Location

United States

Related Subject Headings

  • United States
  • Societies, Medical
  • Humans
  • Heart Failure
  • Cardiovascular System & Hematology
  • Cardiology
  • Cardiac Resynchronization Therapy
  • Cardiac Pacing, Artificial
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology