The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus.
Publication
, Journal Article
Steer, JA; Hill, GB; Wilson, AP
Published in: J Antimicrob Chemother
November 1995
Polymorphonuclear leucocyte (PMN) function is suppressed for several weeks after burn injury, rendering patients susceptible to infection, commonly with Staphylococcus aureus. A study was performed to determine the effects of surgery to the burn wound and antimicrobial prophylaxis with teicoplanin on killing of S. aureus by PMNs taken from burn patients. The bactericidal rate was significantly reduced before surgery compared to controls (P < 0.01 Mann Whitney), but neither surgery nor teicoplanin had any significant additional effect on the bactericidal rate. The bactericidal rate of PMNs did not have any significant effect on clinical outcome following surgery.
Duke Scholars
Published In
J Antimicrob Chemother
DOI
ISSN
0305-7453
Publication Date
November 1995
Volume
36
Issue
5
Start / End Page
851 / 855
Location
England
Related Subject Headings
- Teicoplanin
- Staphylococcus aureus
- Neutrophils
- Middle Aged
- Microbiology
- Male
- Humans
- Female
- Burns
- Anti-Bacterial Agents
Citation
APA
Chicago
ICMJE
MLA
NLM
Steer, J. A., Hill, G. B., & Wilson, A. P. (1995). The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus. J Antimicrob Chemother, 36(5), 851–855. https://doi.org/10.1093/jac/36.5.851
Steer, J. A., G. B. Hill, and A. P. Wilson. “The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus.” J Antimicrob Chemother 36, no. 5 (November 1995): 851–55. https://doi.org/10.1093/jac/36.5.851.
Steer JA, Hill GB, Wilson AP. The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus. J Antimicrob Chemother. 1995 Nov;36(5):851–5.
Steer, J. A., et al. “The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus.” J Antimicrob Chemother, vol. 36, no. 5, Nov. 1995, pp. 851–55. Pubmed, doi:10.1093/jac/36.5.851.
Steer JA, Hill GB, Wilson AP. The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus. J Antimicrob Chemother. 1995 Nov;36(5):851–855.
Published In
J Antimicrob Chemother
DOI
ISSN
0305-7453
Publication Date
November 1995
Volume
36
Issue
5
Start / End Page
851 / 855
Location
England
Related Subject Headings
- Teicoplanin
- Staphylococcus aureus
- Neutrophils
- Middle Aged
- Microbiology
- Male
- Humans
- Female
- Burns
- Anti-Bacterial Agents