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The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus.

Publication ,  Journal Article
Steer, JA; Hill, GB; Wilson, AP
Published in: J Antimicrob Chemother
November 1995

Polymorphonuclear leucocyte (PMN) function is suppressed for several weeks after burn injury, rendering patients susceptible to infection, commonly with Staphylococcus aureus. A study was performed to determine the effects of surgery to the burn wound and antimicrobial prophylaxis with teicoplanin on killing of S. aureus by PMNs taken from burn patients. The bactericidal rate was significantly reduced before surgery compared to controls (P < 0.01 Mann Whitney), but neither surgery nor teicoplanin had any significant additional effect on the bactericidal rate. The bactericidal rate of PMNs did not have any significant effect on clinical outcome following surgery.

Duke Scholars

Published In

J Antimicrob Chemother

DOI

ISSN

0305-7453

Publication Date

November 1995

Volume

36

Issue

5

Start / End Page

851 / 855

Location

England

Related Subject Headings

  • Teicoplanin
  • Staphylococcus aureus
  • Neutrophils
  • Middle Aged
  • Microbiology
  • Male
  • Humans
  • Female
  • Burns
  • Anti-Bacterial Agents
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Steer, J. A., Hill, G. B., & Wilson, A. P. (1995). The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus. J Antimicrob Chemother, 36(5), 851–855. https://doi.org/10.1093/jac/36.5.851
Steer, J. A., G. B. Hill, and A. P. Wilson. “The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus.J Antimicrob Chemother 36, no. 5 (November 1995): 851–55. https://doi.org/10.1093/jac/36.5.851.
Steer, J. A., et al. “The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus.J Antimicrob Chemother, vol. 36, no. 5, Nov. 1995, pp. 851–55. Pubmed, doi:10.1093/jac/36.5.851.
Journal cover image

Published In

J Antimicrob Chemother

DOI

ISSN

0305-7453

Publication Date

November 1995

Volume

36

Issue

5

Start / End Page

851 / 855

Location

England

Related Subject Headings

  • Teicoplanin
  • Staphylococcus aureus
  • Neutrophils
  • Middle Aged
  • Microbiology
  • Male
  • Humans
  • Female
  • Burns
  • Anti-Bacterial Agents