The human genetics of eating disorders lessons from the leptin/melanocortin system.


Journal Article (Review)

Genetic analysis of eating disorders is complex phenotypically and genotypically. As seen in the leptin/melanocortin system, however, the results can lead to a deeper understanding and to new therapies. Benefits are expected for eating disorders that stem from genetic and psychologic causes. Finally, an awareness of possible genetic causes of eating disorders will help determine the causes--and thus the treatments--in children and adolescents with eating disorders, as exemplified by obese patients with mutations in the POMC, PC1, leptin, and MC4R loci.

Full Text

Cited Authors

  • Costa, JL; Brennen, MB; Hochgeschwender, U

Published Date

  • April 2002

Published In

Volume / Issue

  • 11 / 2

Start / End Page

  • 387 - 397

PubMed ID

  • 12109327

Pubmed Central ID

  • 12109327

Electronic International Standard Serial Number (EISSN)

  • 1558-0490

International Standard Serial Number (ISSN)

  • 1056-4993

Digital Object Identifier (DOI)

  • 10.1016/s1056-4993(01)00013-x


  • eng