A trial of outpatient chemotherapy for recurrent head and neck tumors.

Journal Article (Clinical Trial;Journal Article)

A four-drug combination chemotherapy (bleomycin-methotrexate-vinblastine-CCNU) had been used in 38 evaluable patients with recurrent squamous cell carcinoma of the head and neck region on an outpatient basis. A large number of these patients had carcinoma of the oral cavity (45% of total). Nineteen patients (50%) responded to this regimen with a greater than or equal to 50% regression of their measured tumors. The median survival of all patients was 34 weeks. There was one chemotherapy-related death and the overall toxicity was mild. This convenient regimen can be considered a useful alternative to more aggressive therapy.

Full Text

Duke Authors

Cited Authors

  • Huang, AT; Lucas, VS; Baughn, SG; Cole, TB

Published Date

  • April 15, 1980

Published In

Volume / Issue

  • 45 / 8

Start / End Page

  • 2038 - 2041

PubMed ID

  • 6154522

International Standard Serial Number (ISSN)

  • 0008-543X

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19800415)45:8<2038::aid-cncr2820450808>3.0.co;2-1


  • eng

Conference Location

  • United States