3′,4′-Di-o-(-)-camphanoyl-(+)-ciskhellactone and related compounds: A. new class of potent anti-HIV agents
Publication
, Journal Article
Huang, L; Kashiwada, Y; Cosentino, LM; Fan, S; Lee, KH
Published in: Bioorganic and Medicinal Chemistry Letters
February 24, 1994
Dihydroseselin type pyranocumarin derivatives were synthesized based on the discovery that suksdorfin (1) was isolated from Lomatium saksdorfii as an anti-HIV agent. Compound 2 demonstrated extremely potent inhibitory activity against HIV-1 replication in H9 lymphocyte cells with an EC50 value of 0.00041 μM and therapeutic index range of > 78,049 but < 390,244. © 1994.
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Published In
Bioorganic and Medicinal Chemistry Letters
DOI
ISSN
0960-894X
Publication Date
February 24, 1994
Volume
4
Issue
4
Start / End Page
593 / 598
Related Subject Headings
- Medicinal & Biomolecular Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 1115 Pharmacology and Pharmaceutical Sciences
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry
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Huang, L., Kashiwada, Y., Cosentino, L. M., Fan, S., & Lee, K. H. (1994). 3′,4′-Di-o-(-)-camphanoyl-(+)-ciskhellactone and related compounds: A. new class of potent anti-HIV agents. Bioorganic and Medicinal Chemistry Letters, 4(4), 593–598. https://doi.org/10.1016/S0960-894X(01)80161-X
Huang, L., Y. Kashiwada, L. M. Cosentino, S. Fan, and K. H. Lee. “3′,4′-Di-o-(-)-camphanoyl-(+)-ciskhellactone and related compounds: A. new class of potent anti-HIV agents.” Bioorganic and Medicinal Chemistry Letters 4, no. 4 (February 24, 1994): 593–98. https://doi.org/10.1016/S0960-894X(01)80161-X.
Huang L, Kashiwada Y, Cosentino LM, Fan S, Lee KH. 3′,4′-Di-o-(-)-camphanoyl-(+)-ciskhellactone and related compounds: A. new class of potent anti-HIV agents. Bioorganic and Medicinal Chemistry Letters. 1994 Feb 24;4(4):593–8.
Huang, L., et al. “3′,4′-Di-o-(-)-camphanoyl-(+)-ciskhellactone and related compounds: A. new class of potent anti-HIV agents.” Bioorganic and Medicinal Chemistry Letters, vol. 4, no. 4, Feb. 1994, pp. 593–98. Scopus, doi:10.1016/S0960-894X(01)80161-X.
Huang L, Kashiwada Y, Cosentino LM, Fan S, Lee KH. 3′,4′-Di-o-(-)-camphanoyl-(+)-ciskhellactone and related compounds: A. new class of potent anti-HIV agents. Bioorganic and Medicinal Chemistry Letters. 1994 Feb 24;4(4):593–598.
Published In
Bioorganic and Medicinal Chemistry Letters
DOI
ISSN
0960-894X
Publication Date
February 24, 1994
Volume
4
Issue
4
Start / End Page
593 / 598
Related Subject Headings
- Medicinal & Biomolecular Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 1115 Pharmacology and Pharmaceutical Sciences
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry