Anti-VEGF therapies in the clinic

The development and use of antiangiogenesis agents, particularly those targeting vascular endothelial growth factor (VEGF), has become an integral component of anticancer regimens for many tumor types. This reviewis intended to highlight some of the most important clinical successes and failures of anti-VEGF therapies, and where possible, to suggest important lessons that have been learned. This review emphasizes data from agents that have been FDA approved and/or have completed phase III studies. © 2012 Cold Spring Harbor Laboratory Press; all rights reserved.

Duke Scholars

Author Herbert Ira Hurwitz Medicine, Medical Oncology