The impact of lobular histology on breast cancer treatment.

Journal Article (Review)

Lobular neoplasias are a distinct clinical entity with subtle differences in locoregional treatment considerations when compared with ductal cancers. Although overall surgical recommendations do not differ significantly between breast cancers of lobular versus ductal histology, there are important distinctions that should be considered as part of patient care, particularly with respect to recommendations regarding management of the contralateral breast and genetic testing. Because the lobular subtype of breast cancer is underrepresented in studies of molecular prognostic markers, the results of such testing must be interpreted with caution until they are validated specifically in patients with lobular histology. Until then, the mainstay of sound treatment decision-making remains a thorough clinical understanding of the disease and of the factors that can have an impact on outcome.

Full Text

Duke Authors

Cited Authors

  • Hwang, ES

Published Date

  • April 15, 2011

Published In

Volume / Issue

  • 25 / 4

Start / End Page

  • 362 - 365

PubMed ID

  • 21618959

Pubmed Central ID

  • 21618959

International Standard Serial Number (ISSN)

  • 0890-9091

Language

  • eng

Conference Location

  • United States