Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer.

Journal Article (Journal Article)

Nonsentinel lymph nodes (SLNs) are commonly removed at the time of selective sentinel lymphadenectomy (SSL). Their predictive value for the rest of the nodal basin is unknown. A retrospective review of 436 breast cancer patients who underwent SSL between 12/97 and 04/03 at a single institution. One-hundred nineteen patients had non-SLNs removed at SSL; eight were positive (6.7%). Positive non-SLNs predicted that SLNs would also be positive (p = 0.008). There was no difference in rates of additional positive nodes found on completion axillary node dissection between the non-SLN and SLN positive patients (p = 0.62). After adjustment for covariates, the presence of positive non-SLNs was not associated with poorer disease free survival (p = 0.24), time to systemic recurrence (p = 0.57), or overall survival (p = 0.70). Positive non-SLNs removed during SSL are not a significant risk factor for additional positive nodes on completion axillary nodal dissection (CALND) or for worse survival than positive SLNs.

Full Text

Duke Authors

Cited Authors

  • Lang, JE; Liu, L-C; Lu, Y; Jenkins, T; Hwang, SE; Esserman, LJ; Ewing, CA; Alvarado, M; Morita, E; Treseler, P; Leong, SP

Published Date

  • May 2009

Published In

Volume / Issue

  • 15 / 3

Start / End Page

  • 242 - 246

PubMed ID

  • 19645778

Electronic International Standard Serial Number (EISSN)

  • 1524-4741

Digital Object Identifier (DOI)

  • 10.1111/j.1524-4741.2009.00712.x


  • eng

Conference Location

  • United States