Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging.
Journal Article
A single-camera, high-speed, polarization-sensitive, spectral-domain optical-coherence-tomography system was developed to measure the polarization properties of the in vivo human retina. A novel phase-unwrapping method in birefringent media is described to extract the total reflectivity, accumulative retardance, and fast-axis orientation from a specially designed sequence of polarization states incident on the sample. A quarter-wave plate was employed to test the performance of the system. The average error and standard deviation of retardation measurements were 3.2 degrees and 2.3 degrees , respectively, and of the fast-axis orientation 1.2 degrees and 0.7 degrees over the range of 0 degrees -180 degrees . The depolarization properties of the retinal pigment epithelium were clearly observed in both retardance and fast-axis orientation image. A normalized standard deviation of the retardance and of the fast-axis orientation is introduced to segment the polarization-scrambling layer of the retinal pigment epithelium.
Full Text
Duke Authors
Cited Authors
- Zhao, M; Izatt, JA
Published Date
- January 2009
Published In
Volume / Issue
- 34 / 2
Start / End Page
- 205 - 207
PubMed ID
- 19148256
Pubmed Central ID
- 19148256
Electronic International Standard Serial Number (EISSN)
- 1539-4794
International Standard Serial Number (ISSN)
- 0146-9592
Digital Object Identifier (DOI)
- 10.1364/ol.34.000205
Language
- eng