In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography.
Published
Journal Article
There is considerable interest in new methods for the assessment of retinal blood flow for the diagnosis of eye diseases. We present in vivo normal human volumetric retinal flow measurement using Fourier domain Doppler optical coherence tomography. We used a dual-plane scanning pattern to determine the angle between the blood flow and the scanning beam in order to measure total flow velocity. Volumetric flow in each blood vessel around the optic nerve head was integrated in one cardiac cycle in each measurement. Measurements were performed in the right eye of one human subject. The measured venous flow velocity ranged from 16.26 mm/s to 29.7 mm/s. The arterial flow velocity ranged from 38.35 mm/s to 51.13 mm/s. The total retinal venous and arterial flow both added up to approximately 54 microl/min. We believe this is the first demonstration of total retinal blood flow measurement using the OCT technique.
Full Text
Duke Authors
Cited Authors
- Wang, Y; Bower, BA; Izatt, JA; Tan, O; Huang, D
Published Date
- July 2007
Published In
Volume / Issue
- 12 / 4
Start / End Page
- 041215 -
PubMed ID
- 17867804
Pubmed Central ID
- 17867804
Electronic International Standard Serial Number (EISSN)
- 1560-2281
International Standard Serial Number (ISSN)
- 1083-3668
Digital Object Identifier (DOI)
- 10.1117/1.2772871
Language
- eng