Imaging of iris lesions with high-speed optical coherence tomography.

Journal Article (Journal Article)

Background and objectives

To image and measure iris tumors with optical coherence tomography (OCT).

Patients and methods

High-speed (2,000-4,000 axial-scan/sec and 4-16 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosis, and iris melanoma. OCT images were compared with slit-lamp photography and ultrasound biomicroscopy.


OCT at 1.3-micron wavelength could penetrate the full thickness of the iris lesions and allow three-dimensional measurement of lesion size. Internal reflectivity is correlated with pigmentation. OCT is a convenient non-contact method that provides imaging of the clinically important angle structures (scleral spur and angle recess).


OCT is a new imaging modality that complements slit-lamp photography and ultrasound biomicroscopy for serial evaluation of iris

Full Text

Duke Authors

Cited Authors

  • Bakri, SJ; Singh, AD; Lowder, CY; Chalita, MR; Li, Y; Izatt, JA; Rollins, AM; Huang, D

Published Date

  • January 1, 2007

Published In

Volume / Issue

  • 38 / 1

Start / End Page

  • 27 - 34

PubMed ID

  • 17278533

Electronic International Standard Serial Number (EISSN)

  • 1938-2375

International Standard Serial Number (ISSN)

  • 1542-8877

Digital Object Identifier (DOI)

  • 10.3928/15428877-20070101-04


  • eng