Spectral-domain phase microscopy.
Publication
, Journal Article
Choma, MA; Ellerbee, AK; Yang, C; Creazzo, TL; Izatt, JA
Published in: Optics letters
May 2005
Broadband interferometry is an attractive technique for the detection of cellular motions because it provides depth-resolved phase information via coherence gating. We present a phase-sensitive technique called spectral-domain phase microscopy (SDPM). SDPM is a functional extension of spectral-domain optical coherence tomography that allows for the detection of nanometer-scale motions in living cells. The sensitivity of the technique is demonstrated, and its calibration is verified. A shot-noise limit to the displacement sensitivity of this technique is derived. Measurement of cellular dynamics was performed on spontaneously beating cardiomyocytes isolated from chick embryos.
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Optics letters
DOI
EISSN
1539-4794
ISSN
0146-9592
Publication Date
May 2005
Volume
30
Issue
10
Start / End Page
1162 / 1164
Related Subject Headings
- Tomography, Optical Coherence
- Optics
- Myocytes, Cardiac
- Myocardial Contraction
- Microscopy, Phase-Contrast
- Microscopy, Interference
- Equipment Failure Analysis
- Equipment Design
- Chick Embryo
- Cells, Cultured
Citation
APA
Chicago
ICMJE
MLA
NLM
Choma, M. A., Ellerbee, A. K., Yang, C., Creazzo, T. L., & Izatt, J. A. (2005). Spectral-domain phase microscopy. Optics Letters, 30(10), 1162–1164. https://doi.org/10.1364/ol.30.001162
Choma, Michael A., Audrey K. Ellerbee, Changhuei Yang, Tony L. Creazzo, and Joseph A. Izatt. “Spectral-domain phase microscopy.” Optics Letters 30, no. 10 (May 2005): 1162–64. https://doi.org/10.1364/ol.30.001162.
Choma MA, Ellerbee AK, Yang C, Creazzo TL, Izatt JA. Spectral-domain phase microscopy. Optics letters. 2005 May;30(10):1162–4.
Choma, Michael A., et al. “Spectral-domain phase microscopy.” Optics Letters, vol. 30, no. 10, May 2005, pp. 1162–64. Epmc, doi:10.1364/ol.30.001162.
Choma MA, Ellerbee AK, Yang C, Creazzo TL, Izatt JA. Spectral-domain phase microscopy. Optics letters. 2005 May;30(10):1162–1164.
Published In
Optics letters
DOI
EISSN
1539-4794
ISSN
0146-9592
Publication Date
May 2005
Volume
30
Issue
10
Start / End Page
1162 / 1164
Related Subject Headings
- Tomography, Optical Coherence
- Optics
- Myocytes, Cardiac
- Myocardial Contraction
- Microscopy, Phase-Contrast
- Microscopy, Interference
- Equipment Failure Analysis
- Equipment Design
- Chick Embryo
- Cells, Cultured