Dopamine regulation of human speech and bird song: a critical review.

Journal Article (Journal Article;Review)

To understand the neural basis of human speech control, extensive research has been done using a variety of methodologies in a range of experimental models. Nevertheless, several critical questions about learned vocal motor control still remain open. One of them is the mechanism(s) by which neurotransmitters, such as dopamine, modulate speech and song production. In this review, we bring together the two fields of investigations of dopamine action on voice control in humans and songbirds, who share similar behavioral and neural mechanisms for speech and song production. While human studies investigating the role of dopamine in speech control are limited to reports in neurological patients, research on dopaminergic modulation of bird song control has recently expanded our views on how this system might be organized. We discuss the parallels between bird song and human speech from the perspective of dopaminergic control as well as outline important differences between these species.

Full Text

Duke Authors

Cited Authors

  • Simonyan, K; Horwitz, B; Jarvis, ED

Published Date

  • September 2012

Published In

Volume / Issue

  • 122 / 3

Start / End Page

  • 142 - 150

PubMed ID

  • 22284300

Pubmed Central ID

  • PMC3362661

Electronic International Standard Serial Number (EISSN)

  • 1090-2155

Digital Object Identifier (DOI)

  • 10.1016/j.bandl.2011.12.009


  • eng

Conference Location

  • Netherlands