Pharmacogenomics of systemic antifungal agents


Journal Article (Review)

The genomic era offers a multitude of new technologies that may make the promise of personalized medicine a reality for patients in this century. Numerous new antifungal agents have been developed over the past two decades, but use of these agents requires optimization of pharmacokinetics and dosing to achieve efficacy and minimize toxicity. This article reviews the potential application of pharmacogenomics to the use of antifungal agents, highlighting genetic variation that may affect absorption, distribution, metabolism, and elimination of these compounds. © 2009 Current Medicine Group, LLC.

Full Text

Duke Authors

Cited Authors

  • Johnson, MD

Published Date

  • June 1, 2009

Published In

Volume / Issue

  • 3 / 2

Start / End Page

  • 111 - 116

Electronic International Standard Serial Number (EISSN)

  • 1936-377X

International Standard Serial Number (ISSN)

  • 1936-3761

Digital Object Identifier (DOI)

  • 10.1007/s12281-009-0015-9

Citation Source

  • Scopus