Pharmacoeconomics of antifungal pharmacotherapy--challenges and future directions.

Journal Article (Journal Article;Review)

The frequency and severity of invasive fungal infections have been increasingly recognised and new antifungal therapies have expanded the therapeutic armamentarium available to manage such infections. Antifungal agents comprise a significant portion of antibiotic expenditures at major medical centres, prompting adoption of cost-containment measures and treatment guidelines. This paper reviews available data regarding the costs associated with managing fungal infections, including pharmacoeconomic analyses that have been performed in the setting of documented fungal infections, as well as prophylactic and empiric use of antifungal agents. The challenges of performing such studies are discussed, as well as the limitations of published investigations. Finally, recommendations are made regarding the design and implementation of future pharmacoeconomic analyses that can help establish the true costs of managing invasive fungal infections in at-risk patient populations.

Full Text

Duke Authors

Cited Authors

  • Johnson, MD; Kleinberg, M; Danziger, L; Ostrosky-Zeichner, L

Published Date

  • December 2005

Published In

Volume / Issue

  • 6 / 15

Start / End Page

  • 2617 - 2632

PubMed ID

  • 16316301

Electronic International Standard Serial Number (EISSN)

  • 1744-7666

Digital Object Identifier (DOI)

  • 10.1517/14656566.6.15.2617


  • eng

Conference Location

  • England