Towards the validation of a commercial hyperthermia treatment planning system

Journal Article

Recent collaborative study at Duke University to demonstrate the capabilities of new suite of 3D electromagnetic and thermodynamic simulation tools for treatment planning of external hypothermia treatments with Radio Frequency (RF) phased-array heat applicator is discussed. A new approach for improved heating based on treatment planning with electromagnetic simulation software tools, its procedure, benefits and comparison of simulated heating patterns with those measured in two clinical hypothermia treatment of advanced fibrous histiocytoma (soft-tissue sarcoma) tumors is developed. An electromagnetic and thermodynamic co-simulation approach using accurate tissue properties and anatomy from a complete human body model was correlated against direct measurements. Two clinical hypothermia treatments of an advanced soft tissue sarcoma of the leg are simulated and results are compared to simulations and the comparison of simulated. Measured thermal data are shown to have a high degree of correlation if blood perfusion modeling for clinical applications.

Full Text

Duke Authors

Cited Authors

  • Zhen, LI; Maccarini, PF; Arabe, OA; Stakhursky, V; Joines, WT; Stauffer, PR; Vogel, M; Crawford, D

Published Date

  • 2008

Published In

Volume / Issue

  • 51 / 12

Start / End Page

  • 28 - 42

PubMed ID

  • 25324585

Pubmed Central ID

  • 25324585

International Standard Serial Number (ISSN)

  • 0192-6225