MRI for the Assessment of Myocardial Viability

Published

Journal Article (Review)

Accurate distinction between viable and infarcted myocardium is important for assessment of patients who have cardiac dysfunction. Through the technique of delayed-enhancement MRI (DE-MRI), viable and infarcted myocardium can be simultaneously identified in a manner that closely correlates with histopathology findings. This article provides an overview of experimental data establishing the physiologic basis of DE-MRI-evidenced hyperenhancement as a tissue-specific marker of myocardial infarction. Clinical data concerning the utility of transmural extent of hyperenhancement for predicting response to medical and revascularization therapy are reviewed. Studies directly comparing DE-MRI to other viability imaging techniques are presented, and emerging applications for DE-MRI are discussed. © 2007 Elsevier Inc. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Weinsaft, JW; Klem, I; Judd, RM

Published Date

  • November 1, 2007

Published In

Volume / Issue

  • 15 / 4

Start / End Page

  • 505 - 525

International Standard Serial Number (ISSN)

  • 1064-9689

Digital Object Identifier (DOI)

  • 10.1016/j.mric.2007.08.007

Citation Source

  • Scopus