MRI for the assessment of myocardial viability.


Journal Article (Review)

Accurate distinction between viable and infarcted myocardium is important for assessment of patients who have cardiac dysfunction. Through the technique of delayed-enhancement MRI (DE-MRI), viable and infarcted myocardium can be simultaneously identified in a manner that closely correlates with histopathology findings. This article provides an overview of experimental data establishing the physiologic basis of DE-MRI-evidenced hyperenhancement as a tissue-specific marker of myocardial infarction. Clinical data concerning the utility of transmural extent of hyperenhancement for predicting response to medical and revascularization therapy are reviewed. Studies directly comparing DE-MRI to other viability imaging techniques are presented, and emerging applications for DE-MRI are discussed.

Full Text

Duke Authors

Cited Authors

  • Weinsaft, JW; Klem, I; Judd, RM

Published Date

  • February 2007

Published In

Volume / Issue

  • 25 / 1

Start / End Page

  • 35 - v

PubMed ID

  • 17478239

Pubmed Central ID

  • 17478239

International Standard Serial Number (ISSN)

  • 0733-8651

Digital Object Identifier (DOI)

  • 10.1016/j.ccl.2007.02.001


  • eng

Conference Location

  • Netherlands