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Assessment of no-reflow regions using cardiac MRI.

Publication ,  Journal Article
Albert, TSE; Kim, RJ; Judd, RM
Published in: Basic Res Cardiol
September 2006

Ischemic myocardial injury can be broadly characterized as either reversible or irreversible. Within irreversibly injured (infarcted) regions microvascular perfusion can vary from nearly normal to nearly zero, even in the presence of an open infarct-related artery ('no-reflow'). Historically, non-invasive assessment of heterogeneous microvascular perfusion within myocardial infarcts has been problematic. More recently, however, contrast-enhanced MRI has emerged as a promising approach to the examination of these regions in patients with myocardial infarction. In this review we highlight a number of important animal and human studies of no-reflow regions examined using contrast-enhanced MRI. These studies provide evidence that contrast- enhanced MRI can accurately characterize the presence and spatial extent of no-reflow regions, discriminate between areas of necrosis with and without no-reflow, and provide clinically meaningful predictive information regarding left ventricular remodeling and patient outcome.

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Published In

Basic Res Cardiol

DOI

ISSN

0300-8428

Publication Date

September 2006

Volume

101

Issue

5

Start / End Page

383 / 390

Location

Germany

Related Subject Headings

  • Ventricular Remodeling
  • Myocardial Ischemia
  • Magnetic Resonance Imaging
  • Humans
  • Coronary Circulation
  • Cardiovascular System & Hematology
  • Animals
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Albert, T. S. E., Kim, R. J., & Judd, R. M. (2006). Assessment of no-reflow regions using cardiac MRI. Basic Res Cardiol, 101(5), 383–390. https://doi.org/10.1007/s00395-006-0617-0
Albert, Timothy S. E., Raymond J. Kim, and Robert M. Judd. “Assessment of no-reflow regions using cardiac MRI.Basic Res Cardiol 101, no. 5 (September 2006): 383–90. https://doi.org/10.1007/s00395-006-0617-0.
Albert TSE, Kim RJ, Judd RM. Assessment of no-reflow regions using cardiac MRI. Basic Res Cardiol. 2006 Sep;101(5):383–90.
Albert, Timothy S. E., et al. “Assessment of no-reflow regions using cardiac MRI.Basic Res Cardiol, vol. 101, no. 5, Sept. 2006, pp. 383–90. Pubmed, doi:10.1007/s00395-006-0617-0.
Albert TSE, Kim RJ, Judd RM. Assessment of no-reflow regions using cardiac MRI. Basic Res Cardiol. 2006 Sep;101(5):383–390.
Journal cover image

Published In

Basic Res Cardiol

DOI

ISSN

0300-8428

Publication Date

September 2006

Volume

101

Issue

5

Start / End Page

383 / 390

Location

Germany

Related Subject Headings

  • Ventricular Remodeling
  • Myocardial Ischemia
  • Magnetic Resonance Imaging
  • Humans
  • Coronary Circulation
  • Cardiovascular System & Hematology
  • Animals
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology