Magnetic resonance imaging for the assessment of myocardial viability.

Published

Journal Article (Review)

The identification of myocardial viability in the setting of left ventricular (LV) dysfunction is crucial for the prediction of functional recovery following revascularization. Although echocardiography, positron emission tomography (PET), and nuclear imaging have validated roles, recent advances in cardiac magnetic resonance (CMR) technology and availability have led to increased experience in CMR for identification of myocardial viability. CMR has unique advantages in the ability of magnetic resonance spectroscopy (MRS) to measure subcellular components of myocardium, and in the image resolution of magnetic resonance proton imaging. As a result of excellent image resolution and advances in pulse sequences and coil technology, magnetic resonance imaging (MRI) can be used to identify the transmural extent of myocardial infarction (MI) in vivo for the first time. This review of the role of CMR in myocardial viability imaging describes the acute and chronic settings of ventricular dysfunction and concepts regarding the underlying pathophysiology. Recent advances in MRS and MRI are discussed, including the potential for dobutamine MRI to identify viable myocardium and a detailed review of the technique of delayed gadolinium (Gd) contrast hyperenhancement for visualization of viable and nonviable myocardium.

Full Text

Duke Authors

Cited Authors

  • Thomson, LEJ; Kim, RJ; Judd, RM

Published Date

  • June 2004

Published In

Volume / Issue

  • 19 / 6

Start / End Page

  • 771 - 788

PubMed ID

  • 15170783

Pubmed Central ID

  • 15170783

Electronic International Standard Serial Number (EISSN)

  • 1522-2586

International Standard Serial Number (ISSN)

  • 1053-1807

Digital Object Identifier (DOI)

  • 10.1002/jmri.20075

Language

  • eng