A magnetization-driven gradient echo pulse sequence for the study of myocardial perfusion.

Journal Article (Journal Article)

A T1-weighted imaging pulse sequence for contrast-based studies of myocardial perfusion is presented and evaluated in phantoms and in vivo. The sequence is similar to spoiled gradient-recalled echo sequences except that nonselective preparatory RF pulses drive magnetization to steady state prior to image acquisition. Steady state is thus obtained in both tissue and blood resulting in a stable, homogeneous, and dark pre-contrast baseline. Tip angles and timings are chosen so that pixel intensity approximates a linear relation to 1/T1. The dynamic range of signal response to contrast agent concentration is greater than that of an inversion-recovery fast low angle shot sequence. The sequence proposed should be useful for myocardial perfusion studies.

Full Text

Duke Authors

Cited Authors

  • Judd, RM; Reeder, SB; Atalar, E; McVeigh, ER; Zerhouni, EA

Published Date

  • August 1995

Published In

Volume / Issue

  • 34 / 2

Start / End Page

  • 276 - 282

PubMed ID

  • 7476088

Pubmed Central ID

  • PMC2396271

International Standard Serial Number (ISSN)

  • 0740-3194

Digital Object Identifier (DOI)

  • 10.1002/mrm.1910340220


  • eng

Conference Location

  • United States