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Validation of 19F-magnetic resonance determination of myocardial blood volume.

Publication ,  Journal Article
Rottman, GA; Judd, RM; Yin, FC
Published in: Magn Reson Med
October 1995

The use of perfluorochemical (PFC) emulsions to study the myocardial circulation by means of 19F NMR requires that the biodistribution of the PFC be known. The authors tested the hypothesis that PFC particles remain within the myocardial vascular space by infusing rats with both a PFC emulsion and 125I-albumin. Measurement of myocardial vascular volume by 19F NMR and by standard radiotracer analysis of the same tissue yielded concordant values by the two methods, establishing the PFC emulsion as an intravascular agent in this tissue. Perfluorochemical emulsions should be useful for the noninvasive study of myocardial vascular physiology by magnetic resonance.

Duke Scholars

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

October 1995

Volume

34

Issue

4

Start / End Page

628 / 631

Location

United States

Related Subject Headings

  • Tissue Distribution
  • Serum Albumin, Bovine
  • Reproducibility of Results
  • Rats, Wistar
  • Rats
  • Radionuclide Imaging
  • Nuclear Medicine & Medical Imaging
  • Myocardium
  • Male
  • Magnetic Resonance Spectroscopy
 

Citation

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ICMJE
MLA
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Rottman, G. A., Judd, R. M., & Yin, F. C. (1995). Validation of 19F-magnetic resonance determination of myocardial blood volume. Magn Reson Med, 34(4), 628–631. https://doi.org/10.1002/mrm.1910340421
Rottman, G. A., R. M. Judd, and F. C. Yin. “Validation of 19F-magnetic resonance determination of myocardial blood volume.Magn Reson Med 34, no. 4 (October 1995): 628–31. https://doi.org/10.1002/mrm.1910340421.
Rottman GA, Judd RM, Yin FC. Validation of 19F-magnetic resonance determination of myocardial blood volume. Magn Reson Med. 1995 Oct;34(4):628–31.
Rottman, G. A., et al. “Validation of 19F-magnetic resonance determination of myocardial blood volume.Magn Reson Med, vol. 34, no. 4, Oct. 1995, pp. 628–31. Pubmed, doi:10.1002/mrm.1910340421.
Rottman GA, Judd RM, Yin FC. Validation of 19F-magnetic resonance determination of myocardial blood volume. Magn Reson Med. 1995 Oct;34(4):628–631.
Journal cover image

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

October 1995

Volume

34

Issue

4

Start / End Page

628 / 631

Location

United States

Related Subject Headings

  • Tissue Distribution
  • Serum Albumin, Bovine
  • Reproducibility of Results
  • Rats, Wistar
  • Rats
  • Radionuclide Imaging
  • Nuclear Medicine & Medical Imaging
  • Myocardium
  • Male
  • Magnetic Resonance Spectroscopy